According to recent research from Beijing, People’s Republic of China, “The purpose of this study was to examine the effect of a pulpal revascularization procedure for immature necrotic teeth with apical periodontitis (see also <http://www.newsrx.com/library/topics/Periodontitis.html> Periodontitis). Twelve patients, each with an immature permanent tooth with chronic or acute apical periodontitis, were recruited.”

“A triantibiotic mix (ciprofloxacin, metronidazole, and minocycline) was used to disinfect the pulp for 1 week. Then a blood clot was created in the canal, over which grey mineral trioxide aggregate was placed. Patients were recalled periodically. Six patients dropped from the study (as a result of pain or failure to induce bleeding after canal disinfection) and instead received a standard apexification procedure. Another 3 patients did not attend any recall appointments. The remaining teeth (n = 3) were found to exhibit complete root development, with a positive response to pulp testing,” wrote R.Y. Ding and colleagues, Peking University.

The researchers concluded: “Revascularization could be effective for managing immature permanent teeth with apical periodontitis with appropriate case selection. (J Endod 2009;35:745-749).”

Ding and colleagues published their study in the Journal of Endodontics (Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study. Journal of Endodontics, 2009;35(5):745-749).

For additional information, contact C.F. Zhang, Peking University School & Hospital Stomatol, Special Department, Beijing 100081, People’s Republic of China.

Publisher contact information for the Journal of Endodontics is: Elsevier Science Inc., 360 Park Avenue South, New York, NY 10010-1710, USA.

Keywords: People’s Republic of China, Beijing, Anti-Infectives, Blood Clot, Ciprofloxacin, Clinical Trial Research, Clotting, Coagulation, Drugs, Endodontics, Metronidazole, Minocycline, Periodontitis, Pharmaceuticals, Therapy, Treatment, Peking University.

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