According to a study from Brazil, “Recent epidemiologic studies suggest that inflammation is the link between periodontal diseases and cardiovascular complications (see also Periodontitis). This study aimed to evaluate the effects of non-surgical periodontal treatment on plasma levels of inflammatory markers (interleukin [IL]-6, C-reactive protein [CRP], and fibrinogen) in patients with severe periodontitis and refractory arterial hypertension.”

“Twenty-two patients were examined and randomly divided into two groups. The test group was composed of 11 patients (mean age, 48.9 +/- 3.9 years) who received periodontal treatment, whereas the control group had 11 patients (mean age, 49.7 +/- 6.0 years) whose treatment was delayed for 3 months. Demographic and clinical periodontal data were collected, and blood tests were performed to measure the levels of IL-6, CRP, and fibrinogen at baseline and 3 months later. The clinical results showed that the mean percentages of sites with bleeding on probing, probing depth (PD) 4 to 5 mm, PD >= 6 mm, clinical attachment loss (CAL) 4 to 5 mm, and CAL >= 6 mm were significantly reduced in the test group 3 months after periodontal treatment. There were no significant differences between the data at baseline and 3 months in the control group. Periodontal treatment significantly reduced the blood levels of fibrinogen, CRP, and IL-6 in the test group,” wrote F. Vidal and colleagues.

The researchers concluded: “Non-surgical periodontal therapy was effective in improving periodontal clinical data and in reducing the plasma levels of IL-6, CRP, and fibrinogen in hypertensive patients with severe periodontitis. J Periodontol 2009;80:786-791.”

Vidal and colleagues published their study in the Journal of Periodontology (Periodontal Therapy Reduces Plasma Levels of Interleukin-6, C-Reactive Protein, and Fibrinogen in Patients With Severe Periodontitis and Refractory Arterial Hypertension. Journal of Periodontology, 2009;80(5):786-791).

For more information, contact R.G. Fischer, University of Estado Rio De Janeiro, Faculty Odontology, Dept. of Periodontology, Blvd. 28 Setembro, 157 Vila Isabel, BR-20551030 Rio De Janeiro, Brazil.

Publisher contact information for the Journal of Periodontology is: American Acad Periodontology, 737 North Michigan Avenue, Suite 800, Chicago, IL 60611-2690, USA.

Keywords: Brazil, Biotechnology, C Reactive Protein, Cardiology, Cardiovascular Disease, Clinical Trial Research, Hypertension, Inflammation, Periodontal Disease, Periodontitis, Periodontology, Proteomics, Therapy, Treatment.

This article was prepared by Obesity, Fitness & Wellness Week editors from staff and other reports. Copyright 2009, Obesity, Fitness & Wellness Week via NewsRx.com.

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